Vancomycin Injection 500mg

Vancomycin Injection 500mg About

Vancomycin  Injection 500mg 

Product Name: Vancomycin  Injection 250mg

Composition:
Vancomycin (as HCl) 250mg/vial, 1g/vial;
 lyophilized pwdfor IV infusion after reconstitution and dilution.

Indications for Vancomycin Injection:

Serious or severe infections due to susceptible methicillin-resistant (beta-lactam-resistant) staphylococci in penicillin-allergic patients; patients who cannot receive or have failed to respond to other drugs, including penicillins and cephalosporins; and for infections due to vancomycin-susceptible organisms resistant to other antimicrobials. Staphylococcal endocarditis, including septicemia, and infections of the lower respiratory tract, bone, and skin and skin structure. Streptococcal endocarditis due to S. viridans or S. bovis as monotherapy or in combination with an aminoglycoside.

Adult:

Give by intermittent IV infusion over at least 60 minutes or at a rate of 10mg/min or less, whichever is longer. 2g/day in divided doses (500mg every 6 hours or 1g every 12 hours). Renal impairment: adjust or reduce dose, obesity; see literature.

Children:

Give by intermittent IV infusion over at least 60 minutes. Neonates: 1 month: initially 15mg/kg, then 10mg/kg every 12 hours (for neonates in the 1^st week of life) and every 8 hours thereafter (up to 1 month of age). >1 month: 10mg/kg per dose every 6 hours. Renal impairment: adjust or reduce dose, obesity; see literature.

Warnings/Precautions:

Not for prophylaxis of endophthalmitis. Renal insufficiency. Monitor hearing, blood, renal function. Monitor vancomycin serum concentrations closely. Elderly. Debilitated. Pregnancy. Nursing mothers.

Interactions:

Monitor with other ototoxic, nephrotoxic, neurotoxic drugs (eg, aminoglycosides, amphotericin B, bacitracin, polymyxin B, colistin, viomycin, cisplatin). Erythema, histamine-like flushing, anaphylactoid reactions may occur with concomitant anesthetic agents.

Pharmacological Class:

Antibiotic.

Adverse Reactions:

Infusion-related events, nausea, drug fever, rash (may be serious, eg, Stevens-Johnson syndrome), ototoxicity, nephrotoxicity, thrombophlebitis, blood dyscrasias; rare: interstitial nephritis, vertigo.

Technical Specifications

Features	WHO-GMP Certified, Highly Effective, Stability, Balanced Composition, Hygienically Packed
Drug Name	venomycin
Dosage Form	Injection
Packaging Type	Vial
Brand	Facmed
Strength	500 mg
Storage Conditions	Store It At Room Temperature

Key Features and Usage

Vancomycin Injection 500mg is mainly indicated for treating serious infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci. The medicine must be administered intravenously, making it suitable exclusively for use in healthcare settings under professional supervision. Its efficacy and prescription-only status ensure it is used where most beneficial.


How to Prepare and Store the Solution

To reconstitute, dissolve the powder in 10 ml sterile water for injection. Once reconstituted, further dilute as required before intravenous infusion. The reconstituted solution should be used within 24 hours if stored at 2C-8C. Always keep the vial protected from light and stored in a cool environment for optimal potency.


Safety and Compatibility Precautions

Vancomycin should not be mixed with other antibiotics in the same IV solution to avoid incompatibility. It is contraindicated in patients with known hypersensitivity to vancomycin. Use only as directed by a healthcare professional, who will determine the correct dosage based on your condition and age.