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Terbutaline Sulphate Ambroxol Hydrochloride and Guaiphenesin

Terbutaline Sulphate Ambroxol Hydrochloride and Guaiphenesin Specification

Indication
It is a combination of Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin. Terbutaline is a selective beta2 -adrenergic agonist which predominantly stimulates beta2-receptors, thus producing relaxation of bronchial smoothmuscle. Ambroxol possesses mucokinetic (improvement in mucus transport) and secretolytic (liquifies secretions) properties. It promotes the removal of tenacious secretions in the respiratory tract and reduces mucus stasis (arresting the secretion of mucus). Besides that, Ambroxol also exhibits anti-oxidant activity. Guaiphenesin, by increasing respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant. Another possible mechanism by which it acts is by increasing the water bonding in the sputum, thereby decreasing its viscosity and leading to an increase in mucokinesis. Guaiphenesin is effective in both productive and nonproductive coughs.

Origin of Medicine
India

Dosage Form
Liquid

Pacakaging (Quantity Per Box)
100ml per bottle

Salt Composition
It is a combination of Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin. Terbutaline is a selective beta2 -adrenergic agonist which predominantly stimulates beta2-receptors, thus producing relaxation of bronchial smoothmuscle. Ambroxol possesses mucokinetic (improvement in mucus transport) and secretolytic (liquifies secretions) properties. It promotes the removal of tenacious secretions in the respiratory tract and reduces mucus stasis (arresting the secretion of mucus). Besides that, Ambroxol also exhibits anti-oxidant activity. Guaiphenesin, by increasing respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant. Another possible mechanism by which it acts is by increasing the water bonding in the sputum, thereby decreasing its viscosity and leading to an increase in mucokinesis. Guaiphenesin is effective in both productive and nonproductive coughs.

Drug Type
Specific Drug

Ingredients
It is a combination of Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin. Terbutaline is a selective beta2 -adrenergic agonist which predominantly stimulates beta2-receptors, thus producing relaxation of bronchial smoothmuscle. Ambroxol possesses mucokinetic (improvement in mucus transport) and secretolytic (liquifies secretions) properties. It promotes the removal of tenacious secretions in the respiratory tract and reduces mucus stasis (arresting the secretion of mucus). Besides that, Ambroxol also exhibits anti-oxidant activity. Guaiphenesin, by increasing respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant. Another possible mechanism by which it acts is by increasing the water bonding in the sputum, thereby decreasing its viscosity and leading to an increase in mucokinesis. Guaiphenesin is effective in both productive and nonproductive coughs.

Physical Form
Liquid

Function
Anti-Radiation

Recommended For
It is a combination of Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin. Terbutaline is a selective beta2 -adrenergic agonist which predominantly stimulates beta2-receptors, thus producing relaxation of bronchial smoothmuscle. Ambroxol possesses mucokinetic (improvement in mucus transport) and secretolytic (liquifies secretions) properties. It promotes the removal of tenacious secretions in the respiratory tract and reduces mucus stasis (arresting the secretion of mucus). Besides that, Ambroxol also exhibits anti-oxidant activity. Guaiphenesin, by increasing respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant. Another possible mechanism by which it acts is by increasing the water bonding in the sputum, thereby decreasing its viscosity and leading to an increase in mucokinesis. Guaiphenesin is effective in both productive and nonproductive coughs.

Dosage
It is a combination of Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin. Terbutaline is a selective beta2 -adrenergic agonist which predominantly stimulates beta2-receptors, thus producing relaxation of bronchial smoothmuscle. Ambroxol possesses mucokinetic (improvement in mucus transport) and secretolytic (liquifies secretions) properties. It promotes the removal of tenacious secretions in the respiratory tract and reduces mucus stasis (arresting the secretion of mucus). Besides that, Ambroxol also exhibits anti-oxidant activity. Guaiphenesin, by increasing respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant. Another possible mechanism by which it acts is by increasing the water bonding in the sputum, thereby decreasing its viscosity and leading to an increase in mucokinesis. Guaiphenesin is effective in both productive and nonproductive coughs.

Dosage Guidelines
As per physician

Suitable For
Suitable For All

Quantity
100ml Container

Storage Instructions
Store it at room temperature

Terbutaline Sulphate Ambroxol Hydrochloride and Guaiphenesin Trade Information

Minimum Order Quantity
500 Bottles

Payment Terms
Cash in Advance (CID)

Supply Ability
500000 Bottles Per Month

Delivery Time
30 Days

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
100ml per bottle with mono carton and customized packaging is also available.

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India

Certifications
WHO, GMP, ISO

About Terbutaline Sulphate Ambroxol Hydrochloride and Guaiphenesin

Product Name: Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin.

Pack Size: 100 ML

It is a combination of Terbutaline Sulphate, Ambroxol Hydrochloride and Guaiphenesin.

Terbutaline is a selective beta2 -adrenergic agonist which predominantly stimulates beta2-receptors, thus producing relaxation of bronchial smoothmuscle.
Ambroxol possesses mucokinetic (improvement in mucus transport) and secretolytic (liquifies secretions) properties. It promotes the removal of tenacious secretions in the respiratory tract and reduces mucus stasis (arresting the secretion of mucus). Besides that, Ambroxol also exhibits anti-oxidant activity.
Guaiphenesin, by increasing respiratory tract fluid, reduces the viscosity of tenacious secretions and acts as an expectorant. Another possible mechanism by which it acts is by increasing the water bonding in the sputum, thereby decreasing its viscosity and leading to an increase in mucokinesis. Guaiphenesin is effective in both productive and nonproductive coughs.

Metabolism: The main metabolite after oral dosing is the sulphate conjugate and also some glucoronide conjugate can be found in the urine.

Ambroxol: Absorption: Ambroxol is rapidly absorbed (70-80%) after oral administration. The time to reach peak plasma concentration is approximately 2 hours.
Distribution:The distribution half-life of ambroxol is around 1.3 hours.
Metabolism: Metabolite is dibromoanthranilic acid (activity unspecified).
Excretion:Excretion is primarily via the kidneys. Renal clearance (rate) is approximately 53 ml/minute; approximately 5-6% of a dose is excreted unchanged in the urine. The elimination half-life of ambroxol is biphasic, with an alpha half-life of 1.3 hours and a beta half-life of 8.8 hours.

Guaiphenesin: Absorption: Guaiphenesin is well absorbed from the gastro-intestinal tract following oral administration, although limited information regarding its pharmacokinetics is available. After the administration of 600 mg Guaiphenesin to healthy adult volunteers, the Cmax was approximately 1.4ug/ml, with tmax occurring approximately 15 minutes after drug administration.
Distribution: No information is available on the distribution of Guaiphenesin in humans. Metabolism and elimination: Guaiphenesin appears to undergo both oxidation and demethylation. Following an oral dose of 600 mg guaifenesin to 3 healthy male volunteers, the was approximately 1 hour and the drug was not detectable in the blood after approximately 8 hours. Pharmacokinetics in Renal/Hepatic Impairment: There have been no specific studies of Guaiphenesin in subjects with renal or hepatic impairment. Caution is therefore recommended when administering this product to subjects with severe renal or hepatic impairment.

DOSAGE AND ADMINISTRATION
Adults 10-20 ml thrice daily Children (6-12 years): 10 ml thrice daily Children (under 6 years): 5-10 ml thrice daily

Other Information
Packaging Information
Packaging can be customized according to the customer requirement.
Pet bottle of 100 ml.

Advanced Triple-Action Formula

Harnessing the benefits of Terbutaline Sulphate, Ambroxol Hydrochloride, and Guaiphenesin, this liquid medicine provides comprehensive respiratory support. Its targeted mechanism relaxes bronchial muscles, breaks down thick mucus, and encourages efficient clearance for maximum symptom relief.

Convenient and Safe Usage

Packaged in convenient 100ml bottles, this liquid formulation is suitable for people of all ages, provided it is used according to a physician's instructions. Simple to dispense and easy to dose, it is designed for safe, effective, and hassle-free administration.

Proper Storage Ensures Potency

To maintain efficacy, store this product at room temperature, away from moisture and direct sunlight in a dry place. Correct storage is essential to preserving the effectiveness and safety of the medicine throughout its shelf life.

FAQ's of Terbutaline Sulphate Ambroxol Hydrochloride and Guaiphenesin:

Q: How should Terbutaline Sulphate, Ambroxol Hydrochloride, and Guaiphenesin liquid be administered?

A: This liquid medication should be taken exactly as directed by your physician. It is typically administered orally using the provided measuring device. Dosage and frequency depend on the patient's age, severity of symptoms, and specific medical recommendation.

Q: What are the main benefits of this combination formulation?

A: This formulation combines relaxant, mucolytic, and expectorant properties. It relaxes bronchial muscles, liquefies stubborn mucus, and facilitates its removal, resulting in easier breathing and relief from both productive and unproductive coughs.

Q: When is the appropriate time to use this medication?

A: This product is indicated for respiratory conditions characterized by bronchospasm, thick mucus, or persistent cough. Use only as per your healthcare professional's advice, usually when symptoms are present or as part of an ongoing treatment plan.

Q: Where should I store the medication for optimum safety?

A: Keep the medicine in a dry place, stored at room temperature, and protect it from moisture and direct sunlight. Always ensure the bottle is tightly closed and out of reach of children.

Q: What is the process by which this medicine helps relieve respiratory symptoms?

A: Terbutaline relaxes airway muscles, Ambroxol thins and mobilizes mucus, and Guaiphenesin makes mucus less viscous and easier to expel. This collaborative action reduces coughing and improves airflow.

Q: Is this medicine suitable for everyone in the family?

A: Yes, the formulation is suitable for all age groups, but it is crucial to follow the exact dosage and usage instructions provided by a healthcare professional.

Q: Can I use this medication with other drugs?

A: Consult your physician before combining this medicine with other drugs, as the interaction potential depends on your health status and other prescriptions you may be taking.

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