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Cyanocobalamin tablets 50mcg

Cyanocobalamin tablets 50mcg
Cyanocobalamin tablets 50mcg
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Product Code : Cyanocobalamin
Brand Name : Cyanocobalamin tablet
Price And Quantity
  • Minimum Order Quantity
  • 1000
  • Unit of Measure
  • Pack/Packs
  • Price Or Price Range
  • INR
Product Specifications
  • Formulations Type
  • General Drugs
  • Formulations Form
  • Tablets
  • Treatments & Functions
  • Treatment of nutritional Vitamin B12 deficiency. Treatment of vitamin B 12 deficiency following partial gastrectomy. Treatment of tropical sprue, alone or with folic acid. Treatment of pernicious anaemia when parenteral administration is not possible or not advised
  • Storage Instructions
  • Dry Place
Product Description

Product name: Cyanocobalamin tablets 50mcg

Cyanocobalamin 50micrograms Tablets

Qualitative and quantitative composition

Each tablet contains 50 micrograms Cyanocobalamin BP.

Recommended Clinical Indications:

Treatment of nutritional Vitamin B12 deficiency.

Treatment of vitamin B 12 deficiency following partial gastrectomy.

Treatment of tropical sprue, alone or with folic acid.

Treatment of pernicious anaemia when parenteral administration is not possible or not advised.

 

Dosage:

 

Adults: - One to three tablets (50 to 150 micrograms) or more daily at the discretion of the physician.

In pernicious anaemia intramuscular therapy is preferable for initial correction of vitamin B12 deficiency. However, if necessary, the oral route may be used to follow this, in which case at least 300 micrograms should be given daily.

Elderly: - The normal dose for adults is appropriate for the elderly.

Children: - One tablet (50 micrograms) daily at the discretion of the physician.

When possible,This medicine doses should be taken between meals.

Method of administration: Oral.

 

Contraindications

Hypersensitivity to the product or any of the excipients.

Special warnings and precautions for use

For pernicious anaemia, an adequate dose must be used and the blood picture must be examined regularly at least every three months for 18 months until stabilised, and then annually.

Indiscriminate administration of this medicine may mask precise diagnosis.

 

Interaction with other medicinal products and other forms of interaction

Absorption may be reduced by Para-aminosalicylic acid, colchinine, biguanides, neomycin, cholestyramine, potassium chloride, methyldopa, and cimetidine.

Patients treated with  may respond poorly to this medicine .

Serum levels of this medicine may be lowered by oral contraceptives. These interactions are unlikely to have clinical significance.

Anti-metabolities and most antibiotics invalidate vitamins B12 assays by microbiological techniques.

 

Pregnancy and lactation

This medicine should not be used to treat megaloblastic anaemia of pregnancy because this is due to folate deficiency.

 Undesirable effects

Sensitisation to this medicine is rare, but may present as an itching exanthema, and exceptionally as anaphylactic shock.

Acneform and bullous eruptions have been reported rarely.

Patients who have become sensitised to this medicine by injection are often able to tolerate the oral route without trouble.

 

Overdose:

Overdosage is unlikely to require treatment.

Pharmacological properties

Pharmacodynamic properties

This medicine contain cyanocobalamin vitamin B 12, which is used for the treatment of pernicious anaemia, and nutritional deficiencies of vitamin B 12 which results in macrocytic anaemia.

Pharmacokinetic properties

The absorption of cobalamins from the gut is dependent upon the glycoprotein intrinsic factor. Cobalamins are transported rapidly into the blood bound to protein, known as transcobalamins. Cobalamins are stored in the liver and excreted in the bile.

 Preclinical safety data

No further relevant data.

Pharmaceutical particulars

 List of excipients

Lactose BP

Maize Starch BP

Magnesium Stearate BP

Purified Water BP

Film coat

Hydroxypropyl Methylcellulose 2910 Ph.Eur

Ethylcellulose Ph Eur

Acetylated Monoglyceride

Speed colour White 27120 Ansteads HSE (Titanium dioxide, talc and polysorbate)

Isopropyl Alcohol BP

Dichloromethane BP

 

Shelf life

36 months in securitaners

24 months in blisters

 

Special precautions for storage

Protect from light.

Store in well closed containers.

Store below 25°C, protected from light.

Packaging customize as per customer requirements.

Trade Information
  • Delivery Time
  • 30 Days
  • Packaging Details
  • Customize as per customer requirements

FACMED PHARMACEUTICALS PVT. LTD.
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